Publications

2024

Rinne, V.; Gröndahl-Yli-Hannuksela, K.; Fair-Mäkelä, R.; Salmi, M.; Rantakari, P.; Lönnberg, T.; Alinikula, J.; Pietikäinen, A.; Hytönen, J. Single-cell transcriptome analysis of the early immune response in the lymph nodes of Borrelia burgdorferi-infected mice. Microbes and Infection 105424 (2024)
https://doi.org/10.1016/j.micinf.2024.105424

Hohenthal U.; Tikkala J.; Rinne V.; Österback R.; Keskitalo A.; Pietikäinen, A.; Hytönen J. Clinical picture and outcome of the first identified case of human Neoehrlichia mikurensis infection in Finland. Ticks Tick Borne Dis 2024, 16 (1), 102395.
https://doi.org/10.1016/j.ttbdis.2024.102395

Sormunen, J.J., Mänttäri, J., Vesterinen, E.J. & Klemola, T.; Blood meal analysis reveals sources of tick-borne pathogens and differences in host utilization of juvenile Ixodes ricinus across urban and sylvatic habitats. Zoonoses and Public Health 2024, 71: 442–450.
https://doi.org/10.1111/zph.13124

Alale, T.Y., Sormunen, J.J., Vesterinen, E.J., Klemola, T., Knott, K.E. & Baltazar-Soares, M.; Genomic signatures of hybridization between Ixodes ricinus and Ixodes persulcatus in natural populations. Ecology and Evolution 2024, 14: e11415.
https://doi.org/10.1002/ece3.11415

Alale, T.Y., Sormunen, J.J., Nzeh, J., Agjei, R.O., Vesterinen, E.J. & Klemola, T.; Public knowledge and awareness of tick-borne pathogens and diseases: A cross-sectional study in Ghana. Current Research in Parasitology & Vector-Borne Diseases 2024, 6: 100228.
https://doi.org/10.1016/j.crpvbd.2024.100228

2023

Sormunen, J. J.; Mäkelä, S.; Klemola, T.; Alale, T. Y.; Vesterinen, E. J. Voles, Shrews and Red Squirrels as Sources of Tick Blood Meals and Tick-Borne Pathogens on an Island in Southwestern Finland. Ticks Tick Borne Dis 2023, 14 (3), 102134.
https://doi.org/10.1016/j.ttbdis.2023.102134

Sormunen, J. J.; Kulha, N.; Alale, T. Y.; Klemola, T.; Sääksjärvi, I. E.; Vesterinen, E. J. For the People by the People: Citizen Science Web Interface for Real‐time Monitoring of Tick Risk Areas in Finland. Ecological Solutions and Evidence 2023, 4 (4).
https://doi.org/10.1002/2688-8319.12294

Sormunen, J. J.; Sääksjärvi, I. E.; Vesterinen, E. J.; Klemola, T. Crowdsourced Tick Observation Data from across 60 Years Reveals Major Increases and Northwards Shifts in Tick Contact Areas in Finland. Sci Rep 2023, 13 (1), 21274. https://doi.org/10.1038/s41598-023-48744-8

2022

Pietikäinen, A.; Backman, I.; Henningsson, A. J.; Hytönen, J. Clinical Performance and Analytical Accuracy of a C6 Peptide-Based Point-of-Care Lateral Flow Immunoassay in Lyme Borreliosis Serology. Diagn Microbiol Infect Dis 2022, 103 (1), 115657.
https://doi.org/10.1016/j.diagmicrobio.2022.115657

Pietikäinen, A.; Glader, O.; Kortela, E.; Kanerva, M.; Oksi, J.; Hytönen, J. Borrelia Burgdorferi Specific Serum and Cerebrospinal Fluid Antibodies in Lyme Neuroborreliosis. Diagn Microbiol Infect Dis 2022, 104 (3), 115782. https://doi.org/10.1016/j.diagmicrobio.2022.115782

2021

Kortela, E.; Kanerva, M. J.; Puustinen, J.; Hurme, S.; Airas, L.; Lauhio, A.; Hohenthal, U.; Jalava-Karvinen, P.; Nieminen, T.; Finnilä, T.; Häggblom, T.; Pietikäinen, A.; Koivisto, M.; Vilhonen, J.; Marttila-Vaara, M.; Hytönen, J.; Oksi, J. Oral Doxycycline Compared to Intravenous Ceftriaxone in the Treatment of Lyme Neuroborreliosis: A Multicenter, Equivalence, Randomized, Open-Label Trial. Clinical Infectious Diseases 2021, 72 (8), 1323–1331. https://doi.org/10.1093/cid/ciaa217

Rouhiainen, M.; Pietikäinen, A.; Kortela, E.; Kanerva, M. J.; Oksi, J.; Hytönen, J. C6 Peptide Enzyme Immunoassay in Lyme Borreliosis Serology. J Microbiol Methods 2021, 180, 106122. https://doi.org/10.1016/j.mimet.2020.106122

Pietikäinen, A.; Åstrand, M.; Cuellar, J.; Glader, O.; Elovaara, H.; Rouhiainen, M.; Salo, J.; Furihata, T.; Salminen, T. A.; Hytönen, J. Conserved Lysine Residues in Decorin Binding Proteins of Borrelia Garinii Are Critical in Adhesion to Human Brain Microvascular Endothelial Cells. Mol Microbiol 2021, 115 (6), 1395–1409. https://doi.org/10.1111/mmi.14687

Sormunen, J. J.; Pakanen, V.-M.; Elo, R.; Mäkelä, S.; Hytönen, J. Absence of Francisella Tularensis in Finnish Ixodes Ricinus and Ixodes Persulcatus Ticks. Ticks Tick Borne Dis 2021, 12 (6), 101809. https://doi.org/10.1016/j.ttbdis.2021.101809

2020

Cuellar, J.; Åstrand, M.; Elovaara, H.; Pietikäinen, A.; Sirén, S.; Liljeblad, A.; Guédez, G.; Salminen, T. A.; Hytönen, J. Structural and Biomolecular Analyses of Borrelia Burgdorferi BmpD Reveal a Substrate-Binding Protein of an ABC-Type Nucleoside Transporter Family. Infect Immun 2020, 88 (4). https://doi.org/10.1128/IAI.00962-19

Feuth, E.; Virtanen, M.; Helve, O.; Hytönen, J.; Sane, J. Lyme Borreliosis in Finland: A Register-Based Linkage Study. BMC Infect Dis 2020, 20 (1), 819.
https://doi.org/10.1186/s12879-020-05555-w