New publication on the UCB-J results of the ASIC-E4 project!

Our results on the synaptic vesicle PET tracer 11C-UCB-J have been published in Alzheimer´s & Dementia: (https://alz-journals.onlinelibrary.wiley.com/doi/pdf/10.1002/alz.14327). We showed that cognitively unimpaired APOE4/4 homozygotes had lower synaptic density in the hippocampus when compared to cognitively unimpaired APOE3/3 carriers. Inspite of the difference in synaptic density, there was no difference in hippocampus volumes, measured from MRI scans.

We warmly thank all our study volunteers for their generous contribution for the project!