PIM kinases shown to regulate stability of nuclear LDHA

 

In our article published in FEBS Journal, we demonstrate that PIM kinases support nuclear LDHA expression and activities by promoting phosphorylation-dependent interactions of LDHA with 14-3-3 proteins, which shield nuclear LDHA from ubiquitin-mediated degradation. To access the article, see http://doi.org/10.1111/febs.16653