Research
Tick Biology, Ecology and Evolution
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Tick Hosts and Pathogen Reservoirs
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Tick Vector Competences
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Experimental TBD Desingns In Vitro
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TBD In Vitro and In Vivo Immunology
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New Biomarkers and Metabolomics in TBD Diagnostics
Metabolomic analysis of small molecules via UHPLC-MS/MS technique offers a powerful tool for detecting biomarkers in tick-borne diseases like Lyme borreliosis. By analyzing biological sample matrices (e.g., serum, cerebrospinal fluid) from patients with acute infection, this technique reveals unique metabolic profiles associated with the disease. Beyond tick-borne diseases, UHPLC-MS/MS can be applied to other infectious diseases, providing a versatile platform for detecting pathogen-specific biomarkers and pathways. This approach holds promise for differentiating between various infections and tracking disease improvement, opening new avenues for precision diagnostics in infectious disease management, complementing current serology assays.
Contacts:
Jukka Hytönen
Maarit Karonen
Ilari Kuukkanen
Picture: Focus-Video
Copyright: University of Turku
New Antibiotics for Lyme Borreliosis
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Emerging TBD Epidemiology in Finland
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