TBD Turku Research

Research

Tick Biology, Ecology and Evolution

Hard ticks in the genus Ixodes, for instance Ixodes ricinus (the sheep or castor bean tick) and Ixodes persulcatus (the taiga tick), have recently increased in abundance in Finland and elsewhere in northern Europe. This has happened in many locations and under different environments, also in urban and suburban areas nearby big cities. Not all of the reasons for these increases have been examined, but a substantial role for the changing climate has commonly been stressed. Shorter and warmer winters, prolonged growing seasons and other climatic changes are suggested to have direct effects on tick and pathogen performance and indirect effects on tick dynamics via density and range shifts in mammalian and avian host animal populations.

Although several tick species are present, at least occasionally, in Finland, only I. ricinus and I. persulcatus are considered as health threats to humans and domestic animals. These two species look superficially similar, and they may occur at same areas and environments. Both species may carry same bacterial, viral and protozoan pathogens, and they also share hosts in nature: e.g. small rodents, hares, deer, raccoon dogs, passerine birds and humans and their companion animals.

More information:

Ticks and tick-borne pathogens in Finland

Tick Hosts and Pathogen Reservoirs

More information coming soon.

Tick Vector Competences

More information coming soon.

Experimental TBD Desingns In Vitro

More information coming soon.

TBD In Vitro and In Vivo Immunology

More information coming soon.

New Biomarkers and Metabolomics in TBD Diagnostics

Metabolomic analysis of small molecules via UHPLC-MS/MS technique offers a powerful tool for detecting biomarkers in tick-borne diseases like Lyme borreliosis. By analyzing biological sample matrices (e.g., serum, cerebrospinal fluid) from patients with acute infection, this technique reveals unique metabolic profiles associated with the disease. Beyond tick-borne diseases, UHPLC-MS/MS can be applied to other infectious diseases, providing a versatile platform for detecting pathogen-specific biomarkers and pathways. This approach holds promise for differentiating between various infections and tracking disease improvement, opening new avenues for precision diagnostics in infectious disease management, complementing current serology assays.

Contacts:
Jukka Hytönen
Maarit Karonen
Ilari Kuukkanen

Aurum building, Department of Chemistry, University of Turku
Picture: Focus-Video
Copyright: University of Turku

New Antibiotics for Lyme Borreliosis

More information coming soon.

Emerging TBD Epidemiology in Finland

More information coming soon.