PIM kinases shown to regulate estrogen-dependent signalingOur recent data indicate that estrogen receptor (ER) alpha is a novel substrate for PIM kinases. Via phosphorylation of serine…
Doctoral dissertation from our group in March“Alan” Kwan Long Mung defended his PhD thesis entitled “Genomic editing to elucidate the effects of PIM kinases on cancer…
Plenty of publicity to our fluorescent nematodesOur article on the ability of fluorescent nematodes to detect indoor air impurities has obtained a lot of visibility in…
Paper published on biomonitoring of indoor air toxins with C. elegansWe have developed indoor air diagnostics with the help of fluorescent strains of transgenic Caenorhabditis elegans nematodes. When forced to either…
PIM kinases shown to regulate stability of nuclear LDHA In our article published in FEBS Journal, we demonstrate that PIM kinases support nuclear LDHA expression and activities by promoting…
Sini´s dissertationSini Eerola initiated her PhD studies in our group and continued them in Tampere under shared supervision of Prof. Tapio…
Poster on recent results together with a video presentationA poster on the ability of PIM kinases to promote metastatic growth of prostate cancer cells has been presented in…
PIM kinases shown to regulate LKB1 and AMPK activitiesOur article on the cross-talk between PIM, LKB1 and AMPK kinases has now been published in Cell Communication and Signaling….
PIM expression levels in prostate cancer have now been thoroughly analysedWe have compared the expression levels of the three PIM family kinases in benign and malignant prostate tissues and shown…
Breast cancer story on differential regulation of Notch family members in pressOur story is now in press in Journal of Biological Chemistry on how PIM-dependent phosphorylation promotes breast cancer cell growth…