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Valikoituja julkaisuja

Houttu N, Vahlberg T, Miles EA, Calder PC, Laitinen K. The impact of fish oil and/or probiotics on serum fatty acids and the interaction with low-grade inflammation in pregnant women with overweight and obesity: secondary analysis of a randomised controlled trial. Br J Nutr. 2024 Jan 28;131(2):296-311. DOI: https://doi.org/10.1017/s0007114523001915

Soukka J, Polari L, Kalliomäki M, Saros L, Laajala TD, Vahlberg T, Toivola MD, Laitinen K. The effect of a fish oil and/or probiotic intervention from early pregnancy onwards on colostrum immune mediators: A randomized, placebo-controlled, double-blinded clinical trial in overweight/obese mothers. Mol Nutr Food Res 2023, e2200446.
DOI: http://doi.org/10.1002/mnfr.202200446

Muhli E, Benchraka C, Lotankar M, Houttu N, Niinikoski H, Lahti L, Laitinen K Aberrations in the early pregnancy serum metabolic profile in women with prediabetes at two years postpartum. Metabolomics 2023;19:20
DOI: https://doi.org/10.1007/s11306-023-01994-z

Alanne S, Koivunimi E, Löyttyniemi E, Laitinen K. Elementary school-aged children’s and parents’ report of health-related quality of life and relationships with lifestyle measures: A cross-sectional study. Nutrients 2023; 15(5): 1264.
DOI: https://doi.org/10.3390/nu15051264

Houttu, N., Benchraka, C., Lotankar, M. Muhli E, Niinikoski H, Lahti L, Laitinen K. Gut microbiota composition and function in pregnancy as determinants of prediabetes at two-year postpartum. Acta Diabetol 2023.
DOI: https://doi.org/10.1007/s00592-023-02064-5

Mäkelä I, Koivuniemi E, Vahlberg T, Raats MM, Laitinen K. Self-Reported Parental Healthy Dietary Behavior Relates to Views on Child Feeding and Health and Diet Quality. Nutrients 2023; 15(4): 1024.
DOI: https://doi.org/10.3390/nu15041024

Saros L, Lind A, Setänen S, Tertti K, Koivuniemi E, Ahtola A, Haataja L, Shivappa N, Hébert JR, Vahlberg T, Laitinen K. Maternal obesity, gestational diabetes mellitus, and diet in association with neurodevelopment of 2-year-old children. Pediatr Res 2023.
DOI: https://doi.org/10.1038/s41390-022-02455-4

Saros L, VahlbergT, Koivuniemi E, Houttu N, Niinikoski H, Tertti K, Laitinen K. Fish oil and/or probiotics intervention in overweight/obese pregnant women and overweight risk in 24-month-old children. J Pediatr Gastroenterol Nutr 2023;76:218-226.
DOI: https://doi.org/10.1097/MPG.0000000000003659

Koivuniemi E, Raats M, Ollila H, Löyttyniemi E, Laitinen K. Characterising the use, users and effects of a health app supporting lifestyle changes in pregnant women. Brit J Nutr 2022 Oct 20:1-38.
DOI: https://doi.org/10.1017/S0007114522003439

Houttu N, Mokkala K, Saleem WT, Virtanen S, Juhila J, Koivuniemi E, Pellonperä O, Tertti K, Loukonen P, Sorsa T, Salonen A, Lahti L, Laitinen K. Potential pathobionts in vaginal microbiota are affected by fish oil and/or probiotics intervention in overweight and obese pregnant women. Biomedicine & Pharmacotherapy 2022;149: 112841.
DOI: https://doi.org/10.1016/j.biopha.2022.112841

Lotankar M, Mokkala K, Houttu N, Koivuniemi E, Sørensen N, Bjørn Nielsen H, Munukka E, Lahti L, Laitinen K. Distinct diet-microbiota-metabolism interactions in overweight and obese pregnant women: a metagenomics approach. Microbiology Spectrum
DOI: https://doi.org/10.1128/spectrum.00893-21

Miles EA, Vahlberg T, Calder PC, Houttu N, Pajunen L, Koivuniemi E, Mokkala K, Laitinen K. Iodine status in pregnant women and infants in Finland. Eur J Nutr 2022;61:2919-2927.
DOI: https://doi.org/10.1007/s00394-022-02852-9

Mokkala K, Gustafsson J, Vahlberg T, Vreugdenhil ACE, Ding L, Shiri-Sverdlov R, Plat J, Laitinen K, Serum CathepsinD in pregnancy: relation with metabolic and inflammatory markers and effects of fish oils and probiotics. Nutrition, Metabolism and Cardiovascular Diseases 2022;32:1292-1300.
DOI: https://doi.org/10.1016/j.numecd.2022.02.011

Koivuniemi E, Hart K, Mazanowska N, Ruggeri S, Egan B, Censi L, Roccaldo R, Mattila L, Buonocore P, Löyttyniemi E, Raats MM, Wielgos M, Laitinen K. Food Supplement Use Differs from the Recommendations in Pregnant Women: A Multinational Survey. Nutrients. 2022 Jul 15;14(14):2909.
DOI: https://doi.org/10.3390/nu14142909

Pajunen L, Korkalo L, Koivuniemi E, Houttu N, Pellonperä O, Mokkala K, Shivappa N, Hébert JR, Vahlberg T, Tertti K, Laitinen K. A healthy dietary pattern with a low inflammatory potential reduces the risk of gestational diabetes mellitus. Eur J Nutr. 2021 Nov 30. Epub ahead of print.
DOI: https://doi.org/10.1007/s00394-021-02749-z

Mokkala K, Vahlberg T, Houttu N, Koivuniemi E, Lahti L, Laitinen K. Impact of combined consumption of fish oil and probiotics on the serum metabolome in pregnant women with overweight or obesity. EBioMedicine 2021;73, 103655.
DOI: https://doi.org/10.1016/j.ebiom.2021.103655   

Koivuniemi E, Nuutinen O, Riskumäki M, Vahlberg T, Laitinen K. Development of a stand-alone index for the assessment of diet quality in elementary school-aged children. Publ Health Nutr, 1-12.
DOI: https://doi.org/10.1017/S1368980021003657

Koivuniemi E, Gustafsson J, Mäkelä I, Koivisto VJ, Vahlberg T, Schwab U, Niinikoski H, Laitinen K. Parental and child factors associated with 2- to 6-year-old children’s diet quality in Finland. J Academy Nutrition Dietetics 2021.
DOI: https://doi.org/10.1016/j.jand.2021.06.014

Hulkkonen P, Kataja E-L, Vahlberg T, Koivuniemi E, Houttu N, Pellonperä O, Mokkala K, Karlsson H, Laitinen K. The efficacy of probiotics and/or n-3 long-chain polyunsaturated fatty acids intervention on maternal prenatal and postnatal depressive and anxiety symptoms among overweight and obese women. J Affect Disord 2021, 289: 21-30; (published online: April 20, 2021).
DOI: https://doi.org/10.1016/j.jad.2021.04.006

Houttu N, Mokkala K, Koivuniemi E, Pellonperä O, Juhila J, Sorsa T, Laitinen K. The impacts of fish oil and/or probiotic intervention on low-grade inflammation, IGFBP-1 and MMP-8 in pregnancy: A randomized, placebo-controlled, double-blind clinical trial. Biomolecules 2021, 11(1), 5; (published online: December 22, 2020).
PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822218/

Pellonperä O, Vahlberg T, Mokkala K, Houttu N, Koivuniemi E, Tertti T, Rönnemaa T, Laitinen K. Weight gain and body composition during pregnancy: a randomized pilot trial with probiotics and/or fish oil. Brit J Nutr 2020 (published online: November 4, 2020).
PubMed: https://pubmed.ncbi.nlm.nih.gov/33143755/

Mokkala K, Juhila J, Houttu N, Sorsa T, Laitinen K. Early pregnancy serum IGFBP-1 relates to lipid profile in overweight and obese women. Heliyon 2020;6: e04788.
PubMed: https://pubmed.ncbi.nlm.nih.gov/32923723/

Pellonperä O, Mokkala K, Houttu N, Vahlberg T, Koivuniemi E, Tertti K, Rönnemaa T, Laitinen K. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes in an at-risk group of overweight and obese women – a randomized, placebo-controlled, double-blind clinical trial. Diabetes Care 2019a; 42(6):1009-1017.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30967436

Pellonperä O, Koivuniemi E, Vahlberg T, et al. Dietary quality influences body composition in overweight and obese pregnant women. Clin Nutr. 2019b;38(4):1613-1619.
PubMed: https://pubmed.ncbi.nlm.nih.gov/30224302/ 

Laitinen K, Mokkala K. Overall dietary quality relates to gut microbiota diversity and abundance. Int J Mol Sci 2019; 20: 1835.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31013927

García-Patterson A, Balsells M, Yamamoto JM, Kellett JE, Solà I, Gich I, van der Beek EM, Hadar E, Castañeda-Gutiérrez E, Heinonen S, Hod M, Laitinen K, Olsen SF, Poston L, Rueda R, Rust P, van Lieshout L, Schelkle B, Murphy HR, Corcoy R. Usual dietary treatment of gestational diabetes mellitus assessed after control diet in randomizedcontrolled trials: subanalysis of a systematic review and meta-analysis.​ Acta Diabetol. 2018.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30328565

Yamamoto JM, Kellett JE, Balsells M, García-Patterson A, Hadar A, Sola I, Gich I, van der Beek EM, Castañeda-Gutiérrez E, Heinonen S, Hod M, Laitinen K, Olsen SF, Poston L, Rueda R, Rust P, van Lieshout L, Schelkle B, Murphy HR, Corcoy R. Gestational diabetes mellitus and diet: A systematic review and meta-analysis of randomized controlled trials examining the impact of modified dietary interventions on maternal glucose control and neonatal birth weight. Diabetes Care 2018;41:1346-1361.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29934478

Vähämiko S, Laiho A, Lund R, Isolauri E, Salminen S, Laitinen K. The impact of probiotic supplementation during pregnancy on DNA methylation of obesity-related genes in mothers and their children. Eur J Nutr. 2018.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29299736

Houttu N, Mokkala K, Laitinen K. Overweight and obesity status in pregnant women are related to intestinal microbiota and serum metabolic and inflammatory profiles. Clin Nutr. 2017. pii: S0261-5614(17)31433-4.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29338886

Mokkala K, Pussinen P, Houttu N, Koivuniemi E, Vahlberg T, Laitinen K. The impact of probiotics and n-3 long-chain polyunsaturated fatty acids on intestinal permeability in pregnancy: a randomized clinical trial. Benef Microbes 2018 Feb 27;9(2):199-208.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/29345158

Mokkala K, Houttu N, Vahlberg T, Munukka E, Rönnemaa T, Laitinen K. Gut microbiota aberrations precede diagnosis of gestational diabetes mellitus. Acta Diabetol 2017.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/28980079

Röytiö H, Mokkala K, Vahlberg T, Laitinen K. Dietary fibre and fat intake in the habitual diet of overweight, pregnant women have different effects on intestinal microbiota richness and species abundance. Brit J Nutr 2017;118:343-352.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/28901891

Mokkala K, Pellonperä O, Röytiö H, Pussinen P, Rönnemaa T, Laitinen K. Increased intestinal permeability, measured by serum zonulin, is associated with metabolic risk markers in overweight pregnant women. Metabolism. 2017 Apr;69:43-50.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/28285651

Mokkala K, Tertti K, Rönnemaa T, Vahlberg T, Laitinen K. Evaluation of serum zonulin for use as an early predictor for gestational diabetes. Nutr Diabetes. 2017 Mar 20;7(3):e253.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/28319108

Mokkala K, Röytiö H, Ekblad U, Laitinen K. Opportunities for probiotics and polyunsaturated fatty acids to improve metabolic health of overweight pregnant women. Benef Microbes. 2017 Feb 7;8(1):3-15.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/27936867

Mokkala K, Röytiö H, Ekblad U, Vähämiko S, Kaartoaho M, Laitinen K. Sikiökautinen ympäristö säätelee elintapasairauksien riskiä. Suomen Lääkärilehti 2016;71:649-654.
https://research.utu.fi/converis/portal/Publication/17861510?auxfun=&lang=fi_FI

Mokkala K, Röytiö H, Munukka E, Pietilä S, Ekblad U, Rönnemaa T, Eerola E, Laiho A, Laitinen K. Gut microbiota richness and composition and dietary intake of overweight pregnant women are related to serum zonulin concentration, a marker for intestinal permeability. J Nutr 2016 Sep;146(9):1694-700.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/27466607

Hautero U, Poussa T, Laitinen K. Simple dietary criteria to improve serum n-3 fatty acid levels of mothers and their infants one month after delivery. Public Health Nutr. 2017 Feb 20(3):534-541.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/27692015

Mokkala K, Laitinen K, Röytiö H. Bifidobacterium lactis 420 and fish oil enhance intestinal epithelial integrity in Caco-2 cells. Nutr Res. 2016 Mar;36:246-52.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/26923511

Röytiö H, Jaakkola J, Hoppu U, Laitinen K. Development and evaluation of a stand-alone index for the assessment of small children’s diet quality. Publ Health Nutr 2015;18:1941-9.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/25584442

Jaakkola J, Isolauri E, Poussa T, Laitinen K. Benefits of repeated individual dietary counselling in long-term weight control in women after delivery. Maternal Child Nutr 2015;11:1041-8.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/24521459

Vähämiko S, Isolauri E, Laitinen K. Weight status and dietary intake determine serum leptin concentrations in pregnant and lactating women and their infants. Br J Nutr. 2013;110:1098-1106
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/23432806

Niinivirta K, Isolauri E, Laakso P, Linderborg K, Poussa T, Laitinen K. Dietary counseling to improve fat quality during pregnancy alters maternal fat intake and infant essential fatty acid status. J Nutr 2011;141:1281-1285.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/21593355

Gage H, Raats M, Williams P, Egan B, Jakobik V, Laitinen K, Martin-Bautista E, Schmid M, Von Rosen-Von Hoewel J, Campoy C, Decsi T, Morgan J, Koletzko B. Developmental origins of health and disease: the views of first time mothers in 5 European countries on the importance of nutritional influences in the first year of life. Am J Clin Nutr. 2011;94:2018S-2024S.
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/21849599

Laitinen K, Poussa T, Isolauri E. Probiotics and dietary counselling contribute to glucose regulation during and after pregnancy: a randomised controlled trial. Brit J Nutr 2009;101:1679-1687.​
PubMed: https://www.ncbi.nlm.nih.gov/pubmed/19017418